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WARNING: Potential risk of hepatotoxicity (toxic for the liver).
I was taking this for insomnia. It was very impressive at assisting sleep onset. I was still playing with dose and timing when I had to quit because my blood test said liver enzymes were high. I pinned down L-THP as the most likely culprit, so I had to stop taking it.
My liver enzymes have since retuened to normal.
I was taking what some people might consider a high dose, 100mg-200mg (0.1g-0.2g). Appearently I didn't do my research well enough. I knew L-THP was hepatotoxic in extremely high doses (i.e. _ 1g), but appearently there are cases hapatotoxicity at normal doses as well.
I recomend people who are taking L-THP administer it SUBLINGUALY (under the tonge) so as to minimize the risk. I would also recomend getting a liver test done, as well as getting urinalysis testing strips (can be found on amazon). Note that sublingual admiistation is generaly far more potent (takes less to get the same effects), but also it exits your system faster (effects don't last as long).
Also, I don't know if it would work in this case, but milk thistle extract can often protect the liver.
Here is a study on the mechanism of hepatotoxicity.
http://www.ncbi.nlm.nih.gov/pubmed/20109541-
Here are some case reports.
http://www.cdc.gov/mmwr/preview/mmwrhtml/00022295.-
htm
I'm not sure what to rate this product, since I'm not currently taking it, so I'm giving it 3 stars for now. I will soon try smaller doses sublingualy, while monitoring my liver, to see if I can have success with this substance. I just wanted people to know about the risk.
Rating:  [3 of 5 Stars!] |
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[5 of 5 Stars!]
